Amcinonide
Amcinonide
Definition
A synthetic glucocorticoid receptor agonist that mimics the metabolic, anti-inflammatory, and immunosuppressive activity of the natural glucocorticoids. Amcinonide interacts with specific corticosteroid receptors and was internalized, which leads to binding of DNA and modification of gene expression. This results in synthesis of anti-inflammatory mediators while inhibiting synthesis of inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions are achieved.
Also known as 1,4-Pregnadiene-2,20-dione-16,17-cyclopentylidenedioxy-9-fluoro-11,21-dihydroxy-21-acetate, AMCINONIDE, CL 34699, Cyclocort, Triamcinolonacetatcyclopentanonid, Visderm — per NCIT
Also identified as
- ATC D07AC11 per RXNORM
- NCIT NCIT:C47389 per NCIT
- SCTID 420859004 per RXNORM
- SCTID 67980007 per RXNORM
- UNII 423W026MA9 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Dermatitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Facial dermatosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Hand dermatosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Leg dermatosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Scalp dermatosis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.