Cilostazol
Cilostazol
Definition
A quinolinone derivative and cellular phosphodiesterase inhibitor, more specific for phosphodiesterase III (PDE III). Although the exact mechanism of action of is unknown, cilostazol and its metabolites appears to inhibit PDE III activity, thereby suppressing cyclic adenosine monophosphate (cAMP) degradation. This results in an increase in cAMP in platelets and blood vessels, leading to inhibition of platelet aggregation and vasodilation.
Also known as 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydro-2(1H)-quinolinone, CILOSTAZOL, Pletal — per NCIT
Also identified as
- ATC B01AC23 per RXNORM
- NCIT NCIT:C1051 per NCIT
- SCTID 116087001 per RXNORM
- SCTID 395239000 per RXNORM
- UNII N7Z035406B per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Intermittent vascular claudication | may treat | MEDRT · Public domain (U.S. Government work) |
| Peripheral vascular disease | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Cardiovascular system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.