Dexchlorpheniramine
Dexchlorpheniramine
Definition
An alkylamine, and first-generation histamine antagonist with anti-allergic activity. Dexchlorpheniramine competitively blocks H1 receptors, thereby preventing the actions of histamine on bronchial smooth muscle, capillaries and gastrointestinal (GI) smooth muscle. The antagonistic action of this agent blocks the activities of endogenous histamine, thereby preventing histamine-induced bronchoconstriction, vasodilation, increased capillary permeability, and GI smooth muscle spasms.
Also known as 2-Pyridinepropanamine, gamma-(4-chlorophenyl)-N,N-dimethyl-, (S)-, Chlo-amine, D-2-(p-Chloro-alpha-(2-dimethylaminoethyl)benzyl)pyridine, D-Chlorpheniramine, DEXCHLORPHENIRAMINE — per NCIT
Also identified as
- ATC R06AB02 per RXNORM
- NCIT NCIT:C61707 per NCIT
- SCTID 16031005 per RXNORM
- SCTID 372663001 per RXNORM
- UNII 3Q9Q0B929N per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Angioedema | may treat | MEDRT · Public domain (U.S. Government work) |
| Perennial allergic rhinitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Seasonal allergic rhinitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Vasomotor rhinitis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nasal cavity | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.