Finasteride
Finasteride
Definition
A synthetic 4-azasteroid compound. Finasteride competitively binds to and inhibits steroid type II 5-alpha-reductase in the prostate gland, liver, and skin, thereby interfering with the enzymatic conversion of testosterone to 5-dihydrotestosterone (DHT) and reducing serum DHT levels. The reduction in serum DHT levels results in diminished stimulation of androgen receptors in the nuclei of prostate cells and, so, diminished prostate cell proliferation.
Also known as (5alpha,17beta)-N-(1,1-Dimethylethyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide, Chibro-Proscar, FINASTERIDE, Finastid, MK 906, Pro-Cure, Propecia, Propeshia, Proscar, Prostide, Urprosan — per NCIT
Also identified as
- ATC D11AX10 per RXNORM
- ATC G04CB01 per RXNORM
- NCIT NCIT:C1099 per NCIT
- SCTID 109035006 per RXNORM
- SCTID 386963006 per RXNORM
- UNII 57GNO57U7G per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Alopecia | may treat | MEDRT · Public domain (U.S. Government work) |
| Benign prostatic hyperplasia | may treat | MEDRT · Public domain (U.S. Government work) |
| Prostate cancer | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Genitourinary system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Hair | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Male reproductive system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Prostate | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Reproductive system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
6 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.