Lamotrigine
Lamotrigine
Definition
A synthetic phenyltriazine with antiepileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid, an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake. (NCI04)
Also known as Lamictal, LAMOTRIGINE — per NCIT
Also identified as
- ATC N03AX09 per RXNORM
- NCIT NCIT:C38703 per NCIT
- SCTID 387562000 per RXNORM
- SCTID 96195007 per RXNORM
- UNII U3H27498KS per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Bipolar disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Focal epilepsy | may treat | MEDRT · Public domain (U.S. Government work) |
| Lennox-Gastaut syndrome | may treat | MEDRT · Public domain (U.S. Government work) |
| Visual epilepsy | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Brain | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.