Calcipotriene

Definition

A synthetic vitamin D derivative usually formulated for topical dermatological use, antipsoriatic Calcipotriene (calcipotriol) competes equally with active 1,25-hydroxy-2D3 (the natural form of vitamin D) for 1,25-hydroxy-2D3 receptors in regulating cell proliferation and differentiation. It induces differentiation and suppresses proliferation of keratinocytes, reversing abnormal keratinocyte changes in psoriasis, and leads to normalization of epidermal growth. (NCI04)

NCIT:C28900 · NCI Thesaurus OBO Edition · CC BY 4.0

Also known as CALCIPOTRIENE, Calcipotriol, Dovonex — per NCIT

Also identified as

ATC D05AX02 per RXNORM
NCIT NCIT:C28900 per NCIT
SCTID 126232005 per RXNORM
SCTID 395766004 per RXNORM
UNII 143NQ3779B per RXNORM

Indications

Disease	Relation	Source
Psoriasis	may treat	MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ	Side effect / interaction	Source
Skin of body	may treat a disease of this organ	DERIVED · CC BY 4.0

1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.