Mecobalamin
Mecobalamin
Definition
A synthetic and active form of vitamin B12 that can cross the blood brain barrier without biotransformation, that may be used to treat or prevent vitamin B12 deficiency and its complications. Upon administration, mecobalamin is able to replace endogenous vitamin B12, increase vitamin B12 levels and improve vitamin B12 deficiency. Vitamin B12 is necessary for hematopoiesis, neural metabolism, DNA and RNA production, and carbohydrate, fat, and protein metabolism. It improves iron functions in the metabolic cycle and assists folic acid in choline synthesis. Its metabolism is interconnected with that of folic acid.
Also known as Mecobalamin, METHYLCOBALAMIN, Vitamin B12 — per NCIT
Also identified as
- ATC B03BA05 per RXNORM
- NCIT NCIT:C173805 per NCIT
- SCTID 259512006 per RXNORM
- SCTID 714678000 per RXNORM
- UNII BR1SN1JS2W per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Vitamin B12 deficiency | may prevent | MEDRT · Public domain (U.S. Government work) |
| Alcoholic polyneuropathy | may treat | MEDRT · Public domain (U.S. Government work) |
| Diabetic neuropathy | may treat | MEDRT · Public domain (U.S. Government work) |
| Multiple sclerosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Pernicious anemia | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.