Oxaprozin
Oxaprozin
Definition
A nonsteroidal anti-inflammatory drug (NSAID) derivative of oxazole-propionic acid with analgesic and antipyretic properties. As a first generation NSAID inhibitor, oxaprozin binds to and inactivates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of arachidonic acid to pro-inflammatory prostaglandins. When inhibiting COX-2, this agent may be effective in relieving pain and inflammation; when inhibiting COX-1, it may produce unacceptable gastrointestinal side effects. (NCI04)
Also known as 4,5-Diphenyl-2-oxazolepropionic Acid, Daypro, OXAPROZIN, Wy 21743 — per NCIT
Also identified as
- ATC M01AE12 per RXNORM
- NCIT NCIT:C29307 per NCIT
- SCTID 108518005 per RXNORM
- SCTID 386031002 per RXNORM
- UNII MHJ80W9LRB per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Juvenile idiopathic arthritis | may treat | MEDRT · Public domain (U.S. Government work) |
| Osteoarthritis | may treat | MEDRT · Public domain (U.S. Government work) |
| Rheumatoid arthritis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Bone element | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Musculoskeletal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Skeletal joint | may treat a disease of this organ | DERIVED · CC BY 4.0 |
3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.