Oxcarbazepine

Definition

A dibenzazepine carboxamide derivative with an anticonvulsant property. As a prodrug, oxcarbazepine is converted to its active metabolite, 10-monohydroxy. Although the mechanism of action has not been fully elucidated, electrophysiological studies indicate this agent blocks voltage-gated sodium channels, thereby stabilizing hyper-excited neural membranes, inhibiting repetitive neuronal firing, and decreasing the propagation of synaptic impulses.

NCIT:C47643 · NCI Thesaurus OBO Edition · CC BY 4.0

Also known as 10,11-Dihydro-10-oxo-5H-dibenz(b,f)azepine-5-carboxamide, OXCARBAZEPINE, Trileptal — per NCIT

Also identified as

ATC N03AF02 per RXNORM
NCIT NCIT:C47643 per NCIT
SCTID 116511002 per RXNORM
SCTID 387025007 per RXNORM
UNII VZI5B1W380 per RXNORM

Indications

Disease	Relation	Source
Focal epilepsy	may treat	MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ	Side effect / interaction	Source
Brain	may treat a disease of this organ	DERIVED · CC BY 4.0
Central nervous system	may treat a disease of this organ	DERIVED · CC BY 4.0
Nervous system	may treat a disease of this organ	DERIVED · CC BY 4.0

3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.