Foscarnet
ATC Code
J05AD01
Foscarnet
Definition
A synthetic organic analog of inorganic pyrophosphate with activity against several types of viruses, but primarily used for the treatment of cytomegalovirus retinitis. Foscarnet selectively blocks the pyrophosphate binding site of virus-specific DNA polymerases at concentrations that do not affect cellular DNA polymerases. Because this agent crosses the blood brain barrier, it may be used in the treatment of viral infections of the central nervous system.
Also known as Carboxyphosphonic Acid, FOSCARNET, Phosphonocarboxylic Acid, Phosphonoformate, Phosphonoformic Acid — per NCIT
Also identified as
- ATC J05AD01 per RXNORM
- NCIT NCIT:C71630 per NCIT
- SCTID 372902006 per RXNORM
- SCTID 96099004 per RXNORM
- UNII 364P9RVW4X per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Cytomegalovirus infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Genital herpes | may treat | MEDRT · Public domain (U.S. Government work) |