Estropipate

Estropipate

Definition

A natural estrogenic substance composed of estrone sulfate and piperazine. Estropipate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics.

Also known as Estrone Hydrogen Sulfate compound with Piperazine(1:1), ESTROPIPATE, Ogen, Ortho-Est, Estra-1,3,5(10)-trien-17-one 3-sulphate, compound with Piperazine(1:1), Piperazine, compound with 3-(Sulfooxy)estra-1,3,5(10)-trien-17-one(1:1)(9CI), Sulestrex — per NCIT

Also identified as

Indications

Disease Relation Source
Postmenopausal osteoporosis may prevent MEDRT · Public domain (U.S. Government work)
Premature menopause may prevent MEDRT · Public domain (U.S. Government work)
Hypogonadism may treat MEDRT · Public domain (U.S. Government work)
Premature menopause may treat MEDRT · Public domain (U.S. Government work)
Primary ovarian failure may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Female reproductive system may treat a disease of this organ DERIVED · CC BY 4.0
Genitourinary system may treat a disease of this organ DERIVED · CC BY 4.0
Gonad may treat a disease of this organ DERIVED · CC BY 4.0
Ovaries may treat a disease of this organ DERIVED · CC BY 4.0
Reproductive system may treat a disease of this organ DERIVED · CC BY 4.0

5 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.