Isradipine
Isradipine
Definition
A dihydropyridine calcium channel blockers with antihypertensive and vasodilator activities. Isradipine blocks the calcium entry through the calcium ion channels of coronary and peripheral vascular smooth muscle, thereby dilating coronary arteries and peripheral arterioles. This increases oxygen delivery due to an increased blood flow and reduces oxygen requirements due to decrease in total peripheral resistance. (NCI05)
Also known as 3,5-Pyridinedicarboxylic Acid, 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-, Methyl 1-methylethyl Ester, Dynacirc, Isopropyl methyl(+-)-4-(4-benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate, ISRADIPINE, Lomir — per NCIT
Also identified as
- ATC C08CA03 per RXNORM
- NCIT NCIT:C47577 per NCIT
- SCTID 108533002 per RXNORM
- SCTID 386862002 per RXNORM
- UNII YO1UK1S598 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Hypertensive disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Prinzmetal angina | may treat | MEDRT · Public domain (U.S. Government work) |