Sumatriptan
ATC Code
N02CC01
Sumatriptan
Definition
A sulfonamide triptan with vasoconstrictor activity. Sumatriptan selectively binds to and activates serotonin 5-HT1D receptors in the central nervous system (CNS), thereby constricting cerebral blood vessels. This may lead to a relief in pain from vascular headaches. Sumatriptan may also relieve vascular headaches by decreasing the release of vasoactive neuropeptides from perivascular trigeminal axons in the dura mater during a migraine, by reducing extravasation of plasma proteins, and by decreasing the release of other mediators of inflammation from the trigeminal nerve.
Also known as SUMATRIPTAN — per NCIT
Also identified as
- ATC N02CC01 per RXNORM
- NCIT NCIT:C1240 per NCIT
- SCTID 322822007 per RXNORM
- SCTID 395892000 per RXNORM
- UNII 8R78F6L9VO per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Cluster headache syndrome | may treat | MEDRT · Public domain (U.S. Government work) |
| Migraine | may treat | MEDRT · Public domain (U.S. Government work) |