Terbinafine
Terbinafine
Definition
A synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important component of fungal cell membranes. As a result, this agent disrupts fungal cell membrane synthesis and inhibits fungal growth.
Also known as (E)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene Methanamine, SF 86-327, TERBINAFINE — per NCIT
Also identified as
- ATC D01AE15 per RXNORM
- ATC D01BA02 per RXNORM
- NCIT NCIT:C48019 per NCIT
- SCTID 108925005 per RXNORM
- SCTID 373450007 per RXNORM
- UNII G7RIW8S0XP per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Pityriasis versicolor | may treat | MEDRT · Public domain (U.S. Government work) |
| Tinea pedis | may treat | MEDRT · Public domain (U.S. Government work) |
| Tinea unguium | may treat | MEDRT · Public domain (U.S. Government work) |