Quetiapine
ATC Code
N05AH04
Quetiapine
Definition
A dibenzothiazepine derivative with antipsychotic property. Quetiapine fumarate antagonizes serotonin activity mediated by 5-HT 1A and 5-HT2 receptors. With a lower affinity, this agent also reversibly binds to dopamine D1 and D2 receptors in the mesolimbic and mesocortical areas of the brain leading to decreased psychotic effects, such as hallucinations and delusions. In addition, quetiapine also binds to other alpha-1, alpha-2 adrenergic and histamine H1 receptors.
Also known as QUETIAPINE — per NCIT
Also identified as
- ATC N05AH per NCIT
- NCIT NCIT:C61917 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Autism | may treat | MEDRT · Public domain (U.S. Government work) |
| Bipolar disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Major depressive disorder | may treat | MEDRT · Public domain (U.S. Government work) |