Toremifene

Definition

A nonsteroidal triphenylethylene antiestrogen. Chemically related to tamoxifen, toremifene is a selective estrogen receptor modulator (SERM). This agent binds competitively to estrogen receptors, thereby interfering with estrogen activity. Toremifene also has intrinsic estrogenic properties, which are manifested according to tissue type or species. (NCI04)

Also known as (Z)-2-[4-(4-Chloro-1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine, (Z)-4-Chloro-1,2-diphenyl-1[4-[2-(N,N-dimethylamino)ethoxy]phenyl]-1-butene, Farestone, TOREMIFENE — per NCIT

Also identified as

• ATC L02BA02 per RXNORM
• NCIT NCIT:C1256 per NCIT
• SCTID 387588002 per RXNORM
• SCTID 96378009 per RXNORM
• UNII 7NFE54O27T per RXNORM

Indications