Risperidone
Risperidone
Definition
A benzisoxazole derivative with antipsychotic property. Risperidone selectively antagonizes serotonin (5-HT) effects via cortical 5-HT2 receptor, and, to a lesser extent, competes with dopamine at the limbic dopamine D2 receptor. The antagonism leads to decreased psychotic effects, such as hallucinations and delusions. In addition, risperidone has low to moderate affinity for histamine H1, 5-HT1A, 5-HT1C, and 5-HT1D receptors, while it has weak affinity for dopamine D1 and haloperidol-sensitive sigma site receptors.
Also known as RISPERIDONE — per NCIT
Also identified as
- ATC N05AX per NCIT
- NCIT NCIT:C29416 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Autism | may treat | MEDRT · Public domain (U.S. Government work) |
| Bipolar disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Dementia | may treat | MEDRT · Public domain (U.S. Government work) |
| Tourette syndrome | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Central nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nervous system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.