Nizatidine
ATC Code
A02BA04
Nizatidine
Definition
A competitive and reversible histamine H2-receptor antagonist with antacid activity. Nizatidine inhibits the histamine H2-receptors located on the basolateral membrane of the gastric parietal cell, thereby reducing basal and nocturnal gastric acid secretion, resulting in a reduction in gastric volume, acidity, and amount of gastric acid released in response to stimuli.
Also known as Axid, NIZATIDINE — per NCIT
Also identified as
- ATC A02BA04 per RXNORM
- NCIT NCIT:C29295 per NCIT
- SCTID 108664005 per RXNORM
- SCTID 386887009 per RXNORM
- UNII P41PML4GHR per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Duodenal ulcer | may prevent | MEDRT · Public domain (U.S. Government work) |
| Gastric ulcer | may prevent | MEDRT · Public domain (U.S. Government work) |
| Duodenal ulcer | may treat | MEDRT · Public domain (U.S. Government work) |
| Dyspepsia | may treat | MEDRT · Public domain (U.S. Government work) |
| Gastric ulcer | may treat | MEDRT · Public domain (U.S. Government work) |
| Gastroesophageal reflux disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Helicobacter pylori infectious disease | may treat | MEDRT · Public domain (U.S. Government work) |
| Peptic esophagitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Urticaria | may treat | MEDRT · Public domain (U.S. Government work) |
| Zollinger-Ellison syndrome | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Alimentary part of gastrointestinal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Esophagus | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Small intestine | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Stomach | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Upper digestive tract | may treat a disease of this organ | DERIVED · CC BY 4.0 |
7 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.