Magnesium Citrate
Magnesium Citrate
Definition
The citrate salt of the element magnesium with cathartic activity. The cathartic action of magnesium cations appears to result, in part, from osmotically mediated water retention, which subsequently stimulates peristalsis. In addition, magnesium ions may also stimulate the activity of nitric oxide (NO) synthase and increase the biosynthesis of the phospholipid proinflammatory mediator platelet activating factor (PAF) in the gut. NO may stimulate intestinal secretion via prostaglandin- and cyclic GMP-dependent mechanisms while PAF produces significant stimulation of colonic secretion and gastrointestinal motility.
Also known as Citramag, Citrate of Magnesia, Citroma, CitroMag, MAGNESIUM CITRATE — per NCIT
Also identified as
- ATC A06AD19 per RXNORM
- ATC A12CC04 per RXNORM
- ATC B05CB03 per RXNORM
- NCIT NCIT:C29241 per NCIT
- SCTID 12495006 per RXNORM
- SCTID 387052002 per RXNORM
- UNII RHO26O1T9V per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Magnesium deficiency | may prevent | MEDRT · Public domain (U.S. Government work) |
| Constipation disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Magnesium deficiency | may treat | MEDRT · Public domain (U.S. Government work) |