Imiquimod
Imiquimod
Definition
A synthetic agent with immune response modifying activity. As an immune response modifier (IRM), imiquimod stimulates cytokine production, especially interferon production, and exhibits antitumor activity, particularly against cutaneous cancers. Imiquimod's proapoptotic activity appears to be related to Bcl-2 overexpression in susceptible tumor cells. (NCI04)
Also known as 1H-Imidazo(4,5-c)quinolin-4-amine, 1-(2-methylpropyl)-, 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline, Aldara, IMIQUIMOD, R 837, S 26308, Zyclara — per NCIT
Also identified as
- ATC D06BB10 per RXNORM
- NCIT NCIT:C1431 per NCIT
- SCTID 108939005 per RXNORM
- SCTID 386941002 per RXNORM
- UNII P1QW714R7M per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Actinic keratosis | may treat | MEDRT · Public domain (U.S. Government work) |
| Anogenital human papillomavirus infection | may treat | MEDRT · Public domain (U.S. Government work) |
| Basal cell carcinoma | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.