Ziconotide

ATC Code N02BG08

Ziconotide

Definition

A synthetic, nonopiod, twenty-five amino acid polybasic peptide analogue of an omega-conotoxin derived from the marine snail Conus magus with analgesic activity. Ziconotide appears to block neuronal N-type voltage-sensitive calcium channels (NCCB), inhibiting transmission from pain-sensing primary nociceptors. This agent may exhibit significant analgesic activity in refractory pain.

Also known as Prialt, SNX 111, SNX-111, ZICONOTIDE — per NCIT

Also identified as