Zaleplon

Definition

A nonbenzodiazepine from the pyrazolopyrimidine class with hypnotic, sedative, anxiolytic, and muscle relaxant properties. Zaleplon interacts with the gamma-aminobutyric acid (GABA) -A receptor, thereby affecting the chloride channel ionophore complex and potentiating the inhibitory effects of GABA. In addition, zaleplon binds selectively to the brain omega-1 receptor situated on the alpha subunit of the GABA-A/chloride ion channel receptor complex and potentiates t-butyl-bicyclophosphorothionate (TBPS) binding.

Also known as Sonata, ZALEPLON — per NCIT

Also identified as

• ATC N05CF03 per RXNORM
• NCIT NCIT:C29551 per NCIT
• SCTID 116104009 per RXNORM
• SCTID 387012004 per RXNORM
• UNII S62U433RMH per RXNORM

Indications