Desirudin
ATC Code
B01AE01
Desirudin
Definition
A synthetic recombinant form of the naturally occurring hirudin, the anticoagulant substance found in leech. Desirudin is a selective and almost irreversible inhibitor of thrombin, both free and clot-bound, by blocking its active site. This anticoagulant agent has no effect on other components of the hemostatic system. Desirudin is particularly used to prevent deep vein thrombosis in patients undergoing hip and knee replacement surgery.
Also known as 63-Desulfohirudin(Hirudo medicinalis isoform HV1), CGP 39393, DESIRUDIN, Iprivask — per NCIT
Also identified as
- ATC B01AE01 per RXNORM
- NCIT NCIT:C47473 per NCIT
- SCTID 319718008 per RXNORM
- SCTID 407117009 per RXNORM
- UNII U0JZ726775 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Pulmonary embolism | may prevent | MEDRT · Public domain (U.S. Government work) |
| Venous thromboembolism | may prevent | MEDRT · Public domain (U.S. Government work) |