Verteporfin

Definition

A synthetic light-activated agent with photodynamic activity. Upon systemic administration, verteporfin accumulates in neovessels in the eye and, once stimulated by nonthermal red light in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to neovascular endothelium and blood vessel occlusion. (NCI04)

Also known as Benzoporphyrin Derivative Monoacid Ring A, BPD-MA, VERTEPORFIN, Visudyne — per NCIT

Also identified as

• ATC S01LA01 per RXNORM
• NCIT NCIT:C1014 per NCIT
• SCTID 125708009 per RXNORM
• SCTID 387059006 per RXNORM
• UNII 0X9PA28K43 per RXNORM

Indications