Hyoscyamine

ATC Code A03BA03

Hyoscyamine

Definition

A belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. Hyoscyamine functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as well as the eye, heart, bladder, and gastrointestinal tract. These inhibitory effects cause a decrease in saliva, bronchial mucus, gastric juices, and sweat. Furthermore, its inhibitory action on smooth muscle prevents bladder contraction and decreases gastrointestinal motility.

Also known as (-)-Atropine, (S)-Atropine, Benzeneacetic acid, alpha-(hydroxymethyl)-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (3(S)-endo)-, HYOSCYAMINE — per NCIT

Also identified as

Indications

Disease Relation Source
Irritable bowel syndrome may treat MEDRT · Public domain (U.S. Government work)
Peptic ulcer disease may treat MEDRT · Public domain (U.S. Government work)
Rhinitis may treat MEDRT · Public domain (U.S. Government work)
Toxic or drug-related embryofetopathy may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Alimentary part of gastrointestinal system may treat a disease of this organ DERIVED · CC BY 4.0
Craniocervical region may treat a disease of this organ DERIVED · CC BY 4.0
Intestine may treat a disease of this organ DERIVED · CC BY 4.0
Nasal cavity may treat a disease of this organ DERIVED · CC BY 4.0
Upper digestive tract may treat a disease of this organ DERIVED · CC BY 4.0

5 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.