Pentosan Polysulfate
Pentosan Polysulfate
Definition
A semisynthetic heparin-like glucosaminoglycan. Although its mechanism of action is unknown, pentosan polysulfate may act as a buffer to control cell permeability by preventing irritating solutes from reaching cells coated with it. Administered orally, excreted pentosan polysulfate adheres to the urinary bladder wall, preventing irritants from entering bladder cells and the development or progression of interstitial cystitis (IC), a complication of some chemotherapies. This agent also exhibits anticoagulant and fibrinolytic properties. (NCI04)
Also known as CB-8061, PENTOSAN POLYSULFATE, Xylan Hydrogen Sulfate, Xylan Polysulfate — per NCIT
Also identified as
- NCIT NCIT:C1755 per NCIT
- SCTID 109116008 per RXNORM
- SCTID 372571007 per RXNORM
- UNII F59P8B75R4 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Interstitial cystitis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Genitourinary system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Renal system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Urinary bladder | may treat a disease of this organ | DERIVED · CC BY 4.0 |
3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.