Basiliximab

Definition

A recombinant, chimeric, human-murine monoclonal antibody directed against the alpha subunit of the interleukin-2 receptor (IL-2R alpha) with immunosuppressant activity. Basiliximab selectively binds to and blocks IL-2R alpha, expressed on the surface of activated T-lymphocytes, thereby preventing interleukin-2 binding and inhibiting the interleukin-2-mediated activation of lymphocytes.

Also known as BASILIXIMAB, SDZ-CHI-621, Simulect — per NCIT

Also identified as

• ATC L04AC02 per RXNORM
• NCIT NCIT:C52186 per NCIT
• SCTID 109135008 per RXNORM
• SCTID 386978004 per RXNORM
• UNII 9927MT646M per RXNORM

Indications