Palifermin

Definition

A recombinant form of the endogenous human keratinocyte growth factor with cell growth promoting activity. Palifermin acts in the manner similar to the endogenous keratinocyte growth factor that binds to keratinocyte growth factor receptors on the epithelial cell surface in the lining of mouth and gastrointestinal tract. This results in stimulation of epithelial cell proliferation, differentiation and upregulation of cytoprotective mechanisms.

Also known as Growth Factor, Recombinant Human Keratinocyte, Kepivance, Keratinocyte Growth Factor, Recombinant Human, PALIFERMIN, Recombinant Human Keratinocyte Growth Factor, rhKGF, rhu Keratinocyte Growth Factor — per NCIT

Also identified as

• ATC V03AF08 per RXNORM
• NCIT NCIT:C2455 per NCIT
• SCTID 416470008 per RXNORM
• SCTID 416572003 per RXNORM
• SCTID 417092008 per RXNORM
• SCTID 417550009 per RXNORM
• UNII QMS40680K6 per RXNORM

Indications