Gatifloxacin

Gatifloxacin

Definition

A synthetic 8-methoxyfluoroquinolone with antibacterial activity against a wide range of gram-negative and gram-positive microorganisms. Gatifloxacin exerts its effect through inhibition of DNA gyrase, an enzyme involved in DNA replication, transcription and repair, and inhibition of topoisomerase IV, an enzyme involved in partitioning of chromosomal DNA during bacterial cell division.

Also known as 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxo-quinoline-3-carboxylic acid, AM-1155, BMS-206584-01, Gatiflo, GATIFLOXACIN, Tequin, Zymar — per NCIT

Also identified as

Indications

Disease Relation Source
Bacterial conjunctivitis may treat MEDRT · Public domain (U.S. Government work)
Bacterial pneumonia may treat MEDRT · Public domain (U.S. Government work)
Bronchitis may treat MEDRT · Public domain (U.S. Government work)
Cystitis may treat MEDRT · Public domain (U.S. Government work)
Escherichia coli infection may treat MEDRT · Public domain (U.S. Government work)
Gonorrhea may treat MEDRT · Public domain (U.S. Government work)
Haemophilus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Klebsiella infectious disease may treat MEDRT · Public domain (U.S. Government work)
Proteus infectious disease may treat MEDRT · Public domain (U.S. Government work)
Pyelonephritis may treat MEDRT · Public domain (U.S. Government work)
Salmonellosis may treat MEDRT · Public domain (U.S. Government work)
Sinusitis may treat MEDRT · Public domain (U.S. Government work)
Staphylococcal infection may treat MEDRT · Public domain (U.S. Government work)
Streptococcal infection may treat MEDRT · Public domain (U.S. Government work)
Urinary tract infection may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Adult mammalian kidney may treat a disease of this organ DERIVED · CC BY 4.0
Camera-type eye may treat a disease of this organ DERIVED · CC BY 4.0
Conjunctiva may treat a disease of this organ DERIVED · CC BY 4.0
Craniocervical region may treat a disease of this organ DERIVED · CC BY 4.0
Genitourinary system may treat a disease of this organ DERIVED · CC BY 4.0
Lungs may treat a disease of this organ DERIVED · CC BY 4.0
Ocular adnexa may treat a disease of this organ DERIVED · CC BY 4.0
Renal system may treat a disease of this organ DERIVED · CC BY 4.0
Respiratory system may treat a disease of this organ DERIVED · CC BY 4.0
Urinary bladder may treat a disease of this organ DERIVED · CC BY 4.0

10 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.