Dronedarone
Dronedarone
Definition
An orally bioavailable benzofuran derivative, with anti-arrhythmic activity. Upon oral administration, and although the exact mechanism of action through which dronedarone exerts its anti-arrhythmic effect has not been fully elucidated, it inhibits multiple voltage-gated ion channels, including sodium, potassium, and calcium ion channels, and restores the normal sinus rhythm and reduces heart rate in atrial fibrillation. It also non-competitively antagonizes adrenergic receptors.
Also known as DRONEDARONE — per NCIT
Also identified as
- ATC C01BD07 per RXNORM
- NCIT NCIT:C65485 per NCIT
- SCTID 443195003 per RXNORM
- SCTID 443310000 per RXNORM
- UNII JQZ1L091Y2 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Atrial fibrillation | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Cardiovascular system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.