Exemestane

ATC Code L02BG06

Exemestane

Definition

An irreversible steroidal aromatase inhibitor, with antiestrogen and antineoplastic activities. Upon oral administration, exemestane binds irreversibly to and inhibits the enzyme aromatase, thereby blocking the peripheral aromatization of androgens, including androstenedione and testosterone, to estrogens. This lowers estrogen levels in the blood circulation.

Also known as 6-Methyleneandrosta-1,4-diene-3,17-dione, Aromasin, EXEMESTANE, FCE-24304 — per NCIT

Also identified as

Indications

Disease Relation Source
Breast neoplasm may treat MEDRT · Public domain (U.S. Government work)