Methimazole
ATC Code
H03BB01
Methimazole
Definition
A thioamide inhibitor of the enzyme thyroid peroxidase (TPO), with antithyroid activity. Upon administration, methimazole inhibits the metabolism of iodide and the iodination of tyrosine residues in the thyroid hormone precursor thyroglobulin by TPO; this prevents the synthesis of the thyroid hormones triiodothyronine (T3) and thyroxine (T4).
Also known as METHIMAZOLE, Tapazole — per NCIT
Also identified as
- ATC H03BB per NCIT
- NCIT NCIT:C641 per NCIT
Indications
| Disease | Relation | Source |
|---|---|---|
| Goiter | may treat | MEDRT · Public domain (U.S. Government work) |
| Thyroid crisis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Neck | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Thyroid gland | may treat a disease of this organ | DERIVED · CC BY 4.0 |
3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.