Panitumumab

Definition

A human IgG2kappa monoclonal antibody specific for the epidermal growth factor receptor (EGFR). Monoclonal antibody E7.6.3 binds to the EGFR, blocking the binding of epidermal growth factor and transforming growth factor alpha to EGFR-expressing cancer cells and ultimately inhibiting EGFR-dependent cell activation and proliferation. (NCI)

Also known as ABX-EGF, ABX-EGF Monoclonal Antibody, ABX-EGF, Clone E7.6.3, E7.6.3, Human IgG2K Monoclonal Antibody, MoAb ABX-EGF, MoAb E7.6.3, Monoclonal Antibody ABX-EGF, Monoclonal Antibody E7.6.3, PANITUMUMAB, Vectibix — per NCIT

Also identified as

• ATC L01FE02 per RXNORM
• NCIT NCIT:C1857 per NCIT
• SCTID 423259008 per RXNORM
• SCTID 424401006 per RXNORM
• UNII 6A901E312A per RXNORM

Indications