Desloratadine
Desloratadine
Definition
A long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smooth muscle, capillaries and gastrointestinal smooth muscle, including vasodilation, bronchoconstriction, increased vascular permeability, pain, itching and spasmodic contractions of gastrointestinal smooth muscle. Desloratadine is used to provide symptomatic relieve of allergic symptoms.
Also known as 5H-Benzo(5,6)cyclohepta(1,2-b)pyridine, 8-chloro-6,11-dihydro-11-(4-piperidinylidene)-, Clarinex, DESLORATADINE, Sch 34117 — per NCIT
Also identified as
- ATC R06AX27 per RXNORM
- NCIT NCIT:C47474 per NCIT
- SCTID 134506008 per RXNORM
- SCTID 396015008 per RXNORM
- UNII FVF865388R per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Perennial allergic rhinitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Seasonal allergic rhinitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Urticaria | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Craniocervical region | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Nasal cavity | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Skin of body | may treat a disease of this organ | DERIVED · CC BY 4.0 |
3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.