Valganciclovir
ATC Code
J05AB14
Valganciclovir
Definition
A synthetic prodrug of ganciclovir, a nucleoside analogue of 2'-deoxyguanosine, with antiviral activity. After phosphorylation, valganciclovir is incorporated into DNA, resulting in inhibition of viral DNA polymerase, viral DNA synthesis, and viral replication. (NCI04)
Also known as L-Valine, 2-((2-amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy)-3-hydroxypropyl Ester, VALGANCICLOVIR — per NCIT
Also identified as
- ATC J05AB14 per RXNORM
- NCIT NCIT:C2629 per NCIT
- SCTID 129476000 per RXNORM
- SCTID 395266000 per RXNORM
- UNII GCU97FKN3R per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Cytomegalovirus infection | may prevent | MEDRT · Public domain (U.S. Government work) |
| Cytomegalovirus retinitis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Camera-type eye | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Retina | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.