Travoprost
Travoprost
Definition
A synthetic lipophilic isopropyl ester prodrug of the active compound travoprost free acid, a prostaglandin F2alpha analog with anti-glaucoma property. Upon administration, travoprost is hydrolysed to a free acid by corneal esterases, and then selectively stimulating the prostaglandin F (FP prostanoid) receptor, thereby increasing the uveoscleral outflow which leads to a reduction in intra-ocular pressure.
Also known as 5-Heptenoic Acid, 7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((1E,3R)-3-hydroxy-4-(3-(trifluoromethyl)phenoxy)-1-butenyl)cyclopentyl)-, 1-methylethyl Ester,(5Z)-, AL-6221, Travatan Z, TRAVOPROST — per NCIT
Also identified as
- ATC S01EE04 per RXNORM
- NCIT NCIT:C47766 per NCIT
- SCTID 129493000 per RXNORM
- SCTID 391664000 per RXNORM
- UNII WJ68R08KX9 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Open-angle glaucoma | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Camera-type eye | may treat a disease of this organ | DERIVED · CC BY 4.0 |
1 entry above is marked DERIVED: Atlas Médico inferred it by combining two sourced claims, and no source asserts this link directly. Treat it as a navigation aid, not as a clinical statement.