Eplerenone
ATC Code
C03DA04
Eplerenone
Definition
A selective aldosterone receptor antagonist. Eplerenone binds to the mineralocorticoid receptor and blocks the binding of aldosterone, thereby decreasing sodium resorption and subsequently increasing water outflow. This leads to a decrease in blood pressure. Eplerenone is used in the treatment of hypertension and congestive heart failure.
Also known as 9,11alpha-Epoxy-17-hydroxy-3-oxo-17alpha-pregn-4-ene-7alpha,21-dicarboxylic acid, gamma-lactone, Methyl Ester, EPLERENONE, Inspra — per NCIT
Also identified as
- ATC C03DA04 per RXNORM
- NCIT NCIT:C47513 per NCIT
- SCTID 398699008 per RXNORM
- SCTID 407010008 per RXNORM
- UNII 6995V82D0B per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Hypertensive disorder | may treat | MEDRT · Public domain (U.S. Government work) |
| Systolic heart failure | may treat | MEDRT · Public domain (U.S. Government work) |