Vardenafil

Definition

A benzenesulfonamide derivative and phosphodiesterase type 5 (PDE5) inhibitor with vasodilatory activity. Vardenafil selectively inhibits PDE5, thus inhibiting the degradation of cyclic guanosine monophosphate (cGMP) found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. The inhibition of cGMP degradation results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, prolonging penile erection.

Also known as VARDENAFIL — per NCIT

Also identified as

• ATC G04BE09 per RXNORM
• NCIT NCIT:C66650 per NCIT
• SCTID 404858007 per RXNORM
• SCTID 407979001 per RXNORM
• UNII UCE6F4125H per RXNORM

Indications