Estradiol

ATC Code G03CA03

Estradiol

Definition

The most potent form of the naturally occurring steroid sex hormone in humans, produced by ovary, placenta, testis, and in small amount by adrenal cortex. Estradiol binds to a specific intracellular estrogen receptor located in female organs, breasts, hypothalamus and pituitary. The receptor-ligand complex promotes gene expression necessary for the maintenance of fertility and secondary sexual characteristics in females. In addition, estradiol exhibits mild anabolic and metabolic properties, and increases blood coagulability. Estradiol, the principal intracellular human estrogen, is substantially more active at the cellular level than its metabolites, estrone and estriol.

Also known as (17beta)-Estra-1,3,5(10)-triene-3,17-diol, 17 Beta-Estradiol, 17-beta-Estradiol, Estradiol — per NCIT

Also identified as

Indications

Disease Relation Source
Postmenopausal osteoporosis may prevent MEDRT · Public domain (U.S. Government work)
Breast neoplasm may treat MEDRT · Public domain (U.S. Government work)
Hypogonadism may treat MEDRT · Public domain (U.S. Government work)
Premature menopause may treat MEDRT · Public domain (U.S. Government work)
Primary ovarian failure may treat MEDRT · Public domain (U.S. Government work)
Prostate cancer may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Female reproductive system may treat a disease of this organ DERIVED · CC BY 4.0
Genitourinary system may treat a disease of this organ DERIVED · CC BY 4.0
Gonad may treat a disease of this organ DERIVED · CC BY 4.0
Ovaries may treat a disease of this organ DERIVED · CC BY 4.0
Reproductive system may treat a disease of this organ DERIVED · CC BY 4.0

5 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.