Dornase Alfa
ATC Code
R05CB13
Dornase Alfa
Definition
A recombinant human deoxyribonuclease I (rhDNAse) with selective DNA cleaving activity. Upon intrapleural administration, dornase alfa catalyzes the degradation of extracellular DNA in airway secretions, which can reduce their viscosity. Thus, dornase alfa may both promote the clearing of airway mucus and improve pulmonary function.
Also known as DORNASE ALFA, Pulmozyme, Recombinant Human Deoxyribonuclease I — per NCIT
Also identified as
- ATC R05CB13 per RXNORM
- NCIT NCIT:C81664 per NCIT
- SCTID 108630006 per RXNORM
- SCTID 386882003 per RXNORM
- UNII 953A26OA1Y per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Bronchitis | may treat | MEDRT · Public domain (U.S. Government work) |
| Cystic fibrosis | may treat | MEDRT · Public domain (U.S. Government work) |
Organ Effects
| Organ | Side effect / interaction | Source |
|---|---|---|
| Lungs | may treat a disease of this organ | DERIVED · CC BY 4.0 |
| Respiratory system | may treat a disease of this organ | DERIVED · CC BY 4.0 |
2 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.