Levocetirizine

ATC Code R06AE09

Levocetirizine

Definition

A third generation, non-sedating, selective histamine H1 receptor antagonist, with antihistamine, anti-inflammatory and potential anti-angiogenic activities. Levocetirizine competes with endogenous histamine for binding at peripheral H1-receptor sites on the effector cell surface. This prevents the negative symptoms associated with histamine release and an allergic reaction. In addition, as histamine plays an important role in angiogenesis during an allergic inflammatory reaction, blocking the action of histamine may modulate the expression of proangiogenic factors and thus may prevent angiogenesis. As a third-generation histamine H1 receptor antagonist, levocetirizine has fewer side effects than most second-generation antihistamines.

Also known as LEVOCETIRIZINE — per NCIT

Also identified as

Indications

Disease Relation Source
Perennial allergic rhinitis may treat MEDRT · Public domain (U.S. Government work)
Seasonal allergic rhinitis may treat MEDRT · Public domain (U.S. Government work)
Urticaria may treat MEDRT · Public domain (U.S. Government work)

Organ Effects

Organ Side effect / interaction Source
Craniocervical region may treat a disease of this organ DERIVED · CC BY 4.0
Nasal cavity may treat a disease of this organ DERIVED · CC BY 4.0
Skin of body may treat a disease of this organ DERIVED · CC BY 4.0

3 entries above are marked DERIVED: Atlas Médico inferred them by combining two sourced claims, and no source asserts these links directly. Treat them as a navigation aid, not as a clinical statement.