Prasugrel
ATC Code
B01AC22
Prasugrel
Definition
An orally bioavailable thienopyridine, with antiplatelet activity. Upon oral administration, the active metabolite of prasugrel targets and irreversibly binds to the platelet receptor for adenosine diphosphate (ADP), thereby blocking the binding of ADP to its receptor. This inhibits ADP-mediated activation of the glycoprotein complex GPIIb/IIIa, fibrinogen binding to platelets and platelet adhesion and aggregation. This results in increased bleeding time.
Also known as PRASUGREL — per NCIT
Also identified as
- ATC B01AC22 per RXNORM
- NCIT NCIT:C81566 per NCIT
- SCTID 443129001 per RXNORM
- SCTID 443312008 per RXNORM
- UNII 34K66TBT99 per RXNORM
Indications
| Disease | Relation | Source |
|---|---|---|
| Cerebral infarction | may prevent | MEDRT · Public domain (U.S. Government work) |
| Coronary thrombosis | may prevent | MEDRT · Public domain (U.S. Government work) |
| Myocardial infarction | may prevent | MEDRT · Public domain (U.S. Government work) |