Eltrombopag

Definition

An orally active thrombopoietin receptor agonist with megakaryopoiesis stimulating activity. Eltrombopag binds to and stimulates the platelet thrombopoietin receptor (TPO-R or CD110), a member of the hematopoietin receptor superfamily. Activation of TPO-R leads to the proliferation and differentiation of megakaryocytes, thereby increasing the production of blood platelets.

Also known as ELTROMBOPAG — per NCIT

Also identified as

• ATC B02BX05 per RXNORM
• NCIT NCIT:C71634 per NCIT
• SCTID 432005001 per RXNORM
• SCTID 441995009 per RXNORM
• UNII S56D65XJ9G per RXNORM

Indications