Romiplostim

ATC Code B02BX04

Romiplostim

Definition

A recombinant protein with megakaryopoiesis stimulating activity. Romiplostim mimics endogenous thrombopoietin (TPO), directly binding to and activating the platelet thrombopoietin receptor (TpoR, Mpl, or CD110 antigen), a cytokine receptor belonging to the hematopoietin receptor superfamily. Activation of TpoR stimulates the proliferation and differentiation of megakaryocytes, resulting in an increase in the production of blood platelets.

Also known as AMG 531, Amgen Megakaryopoiesis Protein 2, Nplate, ROMIPLOSTIM — per NCIT

Also identified as