Endocardial cushion

Definition

GO graph seems to suggest this is an endothelium. WP: The endocardial cushions are thought to arise from a subset of endothelial cells that undergo epithelial to mesenchymal transformation, a process whereby these cells break cell-to-cell contacts and migrate into the cardiac jelly (towards to interior of the heart tube). Latest (2010-06-01) new def suggested for GO, added above. Note that EHDAA2 has a more detailed model which we may later adopt. JB: Patterning makes the cushions lay down connective tissue in three domains that force out the local endothelial lining and so the leaflets form

Also known as atrioventricular cushion, AV cushion, cardiac cushion, endocardial cushion tissue — per UBERON

The Endocardial cushion is a part of the Cardiovascular.

Also identified as

• MESH D054089 per UBERON