Irreversible Electroporation

Definition

A non-thermal ablation modality that is used in the treatment of locally advanced soft tissue tumors. This technique uses ultra-short, but strong, electrical fields to create permanent, lethal nanopores in cell membranes, disrupting cellular homeostasis and causing cell death. The technique may be performed intraoperatively, laparoscopically, or percutaneously.

Also known as IRE, Irreversible Electroporation — per NCIT