Ewing sarcoma/peripheral primitive neuroectodermal tumor of bone
Ewing sarcoma/peripheral primitive neuroectodermal tumor of bone
Definition
A spectrum of malignant tumors arising from the bone and characterized morphologically by the presence of small round cells. Ewing sarcoma and peripheral primitive neuroectodermal tumor represent the ends of a spectrum, with Ewing sarcoma lacking evidence of neural differentiation and the markers that characterize the peripheral primitive neuroectodermal tumor. Ewing sarcoma and peripheral primitive neuroectodermal tumor may share cytogenetic abnormalities, proto-oncogene expression, cell culture and immunohistochemical abnormalities. Pain and the presence of a mass are the most common clinical symptoms.
Also known as bone tissue Ewing sarcoma/peripheral primitive neuroectodermal tumor, bone tissue Ewing sarcoma/peripheral primitive neuroectodermal tumour, Ewing sarcoma/peripheral primitive neuroectodermal tumor of bone, Ewing's sarcoma/peripheral primitive neuroectodermal tumor of bone, Ewing's sarcoma/peripheral primitive neuroectodermal tumour of bone — per MONDO
Also identified as
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Bone element | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Bone element | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Connective tissue | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Musculoskeletal system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |