Systemic sclerosis

Definition

A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The two types of systemic scleroderma, limited cutaneous and diffuse cutaneous are classified with focus on the extent of affected skin. A relationship exists between the extent of skin area affected and degree of internal organ/system involvement. Systemic scleroderma can manifest itself in pulmonary fibrosis, Raynaud's syndrome, digestive system telangiectasias, renal hypertension and/or pulmonary hypertension.

Also known as Scleroderma, systemic, SSc, Systemic Scleroderma, systemic sclerosis — per MONDO

Also identified as

• DOID 418 per MONDO
• ICD10CM M34 per MONDO
• ICD9 710.1 per MONDO
• MESH D012595 per MONDO
• NCIT C72070 per MONDO
• Orphanet 90291 per MONDO
• SCTID 89155008 per MONDO
• UMLS C0036421 per MONDO

Drugs indicated