Caffey disease
Caffey disease
Definition
Caffey disease is an osteosclerotic dysplasia characterized by acute inflammation with massive subperiosteal new bone formation usually involving the diaphyses of the long bones, as well as the ribs, mandible, scapulae, and clavicles. The disease is associated with fever, irritability pain and soft tissue swelling, with onset around the age of 2 months and resolving spontaneously by the age of 2 years. However, prenatal disease onset has also been described.
Also known as Caffey disease, infantile cortical hyperostosis — per MONDO
Also identified as
- DOID 4257 per MONDO
- ICD9 756.59 per MONDO
- MESH D006958 per MONDO
- NCIT C118423 per MONDO
- OMIM 114000 per MONDO
- Orphanet 1310 per MONDO
- SCTID 24752008 per MONDO
- UMLS C0020497 per MONDO
Affected Organs
| Organ | Involvement | Source |
|---|---|---|
| Bone element | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Bone element | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |
| Connective tissue | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Musculoskeletal system | Disease Has Associated Anatomic Site | NCIT · CC BY 4.0 |
| Musculoskeletal system | Disease Has Primary Anatomic Site | NCIT · CC BY 4.0 |