Fibrous dysplasia

Fibrous dysplasia

Definition

A genetic, non-inheritable disorder caused by osteoblastic differentiation defects that result in the replacement of bone marrow and trabecular bone by fibrous stroma and immature bone. It usually affects a single bone and less frequently multiple bones. Skull, femur, tibia, and humerus are the most frequently affected bones. It manifests with pain, deformities, and fractures.

Also known as fibrous dysplasia of bone — per MONDO

Also identified as

Affected Organs

Organ Involvement Source
Bone element Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Bone element Disease Has Primary Anatomic Site NCIT · CC BY 4.0
Connective tissue Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Musculoskeletal system Disease Has Associated Anatomic Site NCIT · CC BY 4.0
Musculoskeletal system Disease Has Primary Anatomic Site NCIT · CC BY 4.0